Fig. 1: V. cholerae with a fused chromosome identified in multiple patients and households.

A Schematic representation of the study design; B PFGE results for the putatively fused (light blue) and non-fused (dark blue) chromosomes identified by sequencing. Schizosaccharomyces pombe was used as a DNA size marker and V. cholerae strain N16961 as a well-characterized isolate with two chromosomes. PFGE was conducted twice. PFGE: Pulsed-Field Gel Electrophoresis; Mbp: Mega base pair; Vc: Vibrio cholerae; S. pombe: Schizosaccharomyces pombe. Source data is provided as a Source Data file.