Fig. 2: The electrical performance of the neurorevive-FlexChip.
a–c Impedance and phase of NeuroRevive-FlexChip with the following conditions: bare surface, surface modified with PtNPs, PtNPs/PPy/MWCNTs, PtNPs/PEDOT:PSS/MWCNTs, and PtNPs/PEDOT:PSS/PPy/MWCNTs (n = 3 independent detection sites per group; data are presented as mean ± s.d.; P values: Bare vs. PtNPs, P = 0.0001; PtNPs vs. PtNPs/PPy/MWCNTs, P = 0.1792; PtNPs vs PtNPs/PEDOT:PSS/MWCNTs, P = 0.0008; PtNPs vs PtNPs/PEDOT:PSS/MWCNTs/PPy P = 0.0009; PtNPs/PEDOT:PSS/MWCNTs vs. PtNPs/PEDOT:PSS/MWCNTs/PPy, P = 0.332). d–f SEM image of NeuroRevive-FlexChip with the following conditions: surface modified with PtNPs/PPy/MWCNTs, PtNPs/PEDOT:PSS/MWCNTs, and PtNPs/PEDOT:PSS/PPy/MWCNTs. g–i The CV curves of modified micro-electrodes of NeuroRevive-FlexChip. g PtNPs/PPy/MWCNTs, h PtNPs/PEDOT:PSS/MWCNTs, and i PtNPs/PEDOT:PSS/PPy/MWCNTs. j The CV scanning (0.2–0.6 V) in a 200 μM DA solution of the NeuroRevive-FlexChip. k The double layer capacitance (Cdl) of the PtNPs/PPy/MWCNTs, PtNPs/PEDOT:PSS/MWCNTs and PtNPs/PEDOT:PSS/PPy/MWCNTs modified micro-electrodes of NeuroRevive-FlexChip (n = 3 independent detection sites per group, data are presented as mean ± s.d.). l The charge storage capacity of the PtNPs/PPy/MWCNTs, PtNPs/PEDOT:PSS/MWCNTs and PtNPs/PEDOT:PSS/PPy/MWCNTs modified micro-electrodes of NeuroRevive-FlexChip (n = 3 independent detection sites per group; data are presented as mean ± s.d.; P values: PtNPs/PPy/MWCNTs vs PtNPs/PEDOT:PSS/MWCNTs, P = 0.0048; PtNPs/PEDOT:PSS/MWCNTs vs PtNPs/PEDOT:PSS/PPy/MWCNTs, P = 0.0344; PtNPs/PPy/MWCNTs vs PtNPs/PEDOT:PSS/PPy/MWCNTs, P = 0.0039). Statistical significance was assessed by unpaired two-tailed Student’s t-tests. ns, not significant (p ≥ 0.05); *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.
