Fig. 2: Obesity associated vascular morphogenesis and remodeling in vWAT.
From: Obesity drives depot-specific vascular remodeling in male white adipose tissue
a Bioplanet annotated pathways upregulated in Cap I endothelial cells (ECs). b Gene ontology (GO) analysis showing enriched biological processes in Cap I ECs. c TTRUST transcription factor (TF) analysis predicting upstream regulators in Cap I ECs. d Bioplanet annotated pathways upregulated in Cap II ECs. e GO term analysis showing enriched biological processes in Cap II ECs. f TTRUST TF analysis predicting upstream regulators in Cap II ECs. g Bioplanet predicted pathways upregulated in Cap II when directly compared to Cap I in visceral white adipose tissue (vWAT) ECs. h GO terms enriched in Cap II ECs when compared to Cap I vWAT ECs. i TTRUST TF analysis depicting differentially enriched regulators in Cap II vWAT ECs when compared to Cap I vWAT ECs. j Upregulated pathways k enriched GO terms and l predicted TFs in venous ECs in obese (high fat diet, HFD) vs lean (control diet, CD) vWAT. m Upregulated pathways n enriched GO terms and o predicted TFs in arterial ECs in obese (HFD) vs lean (CD) vWAT. Fisher’s exact test (a-o). All schematics created in BioRender. Hasan, S. (2025) https://BioRender.com/ossmape. Source data are provided as a Source Data file.
