Fig. 7: Fenestrated endothelium in human sWAT.
From: Obesity drives depot-specific vascular remodeling in male white adipose tissue
a Representative confocal images showing ITM2A+ (yellow) endothelial cells (ECs) and CD31+ (red) blood vessels in human subcutaneous white adipose tissue (sWAT) from lean human or patients with obesity. b Representative confocal images showing ITM2A+ (yellow) ECs and CD31+ (red) blood vessels in human visceral white adipose tissue (vWAT) from lean human or patients with obesity. c Quantification of ITM2A+ area normalized to CD31+ area for sWAT (lean donors n = 5, patient with obesity n = 5). d Quantification of ITM2A+ area normalized to CD31+ area for vWAT (lean donors n = 4, patient with obesity n = 5. Schematics created in BioRender. Hasan, S. (2025) https://BioRender.com/4t8j1lu. e Graphical summary of obesity-associated vascular alterations in sWAT and vWAT ECs. Graphical summary created in BioRender. Hasan, S. (2025) https://BioRender.com/5ghaxuk. Scale bars 100 µm. Data represents ± SEM, two-sided Welch’s t-test. Source data are provided as a Source Data file.
