Table 1 Cell cycle- and autophagy-associated accumulation patterns of DiD-LIP and DiD-LNP by cancer cells based on the multi-functional platform
From: Evaluating cell cycle- and autophagy-associated cellular accumulation of lipid-based nanoparticles
Cell line | Dimension | DiD-LIP | DiD-LNP | ||
|---|---|---|---|---|---|
TFI (a.u.) | MFI (a.u.) | TFI (a.u.) | MFI (a.u.) | ||
WT PIP-FUCCI | 2D | M < G1 ≈ S < G2 | M < G1 ≈ S ≈ G2 | M < G1 ≈ S < G2 | M < G1 ≈ S < G2 |
WT PIP-FUCCI | 3D | M ( ≈ G1) < (G1 ≈ ) S < G2 | M < G1 ≈ S ≈ G2 | M < G1 ≈ S < G2 | M < G1 < S < G2 |
ATG7 KO PIP-FUCCI | 2D | M < G1 ≈ S < G2 | M < G1 ≈ S ≈ G2 | M < G1 ≈ S < G2 | M < G1 ≈ S ≈ G2 |
ATG7 KO PIP-FUCCI | 3D | M < G1 < S < G2 | M < G1 ≈ S ≈ G2 | M ≈ G1 ≈ S < G2 | M < (G1 ≈ ) S < (G1 ≈ ) G2 |
