Fig. 3: Scope for cobalt-catalyzed enantioselective reductive coupling of alkynes and cyclobutenes.
From: Pathway-divergent coupling of alkynes and cyclobutenes through enantioselective cobalt catalysis

aThe reactions were conducted with 10 mol % CoI2 and 10 mol % 4h in the presence of 2.5 equiv of Hantzsch ester instead of H2O. bThe reactions were performed with 10 mol % CoI2 and 10 mol % 4h in the presence of 100 equiv of H2O for 48 h. 4CzIPN, 1,2,3,5-tetrakis(carbazole-9-yl)−4,6-dicyanobenzene.