Fig. 5: Gram-scale reaction and functionalization.
From: Pathway-divergent coupling of alkynes and cyclobutenes through enantioselective cobalt catalysis

a Gram-scale reaction. b Functionalization of the reductive coupling product. c Functionalization of the [2 + 2] cycloaddition product. d Desilylation. DME dimethoxyethane, DMM dimethoxymethane.