Fig. 1: Study design and experimental workflow.

a Three meningioma cohorts, comprising three different medical centers, were used for meningioma copy number analyses. The discovery cohort was used for training of all models, and the external test cohorts were used for model validation. b Workflow diagram of analyses performed, illustrating the identification of size-dependent CNAs, model building and validation, sliding window binned CNA analyses, and co-occurrence analyses. Source data are provided as a Source Data file.