Fig. 3: Staged in vitro degradation behavior of the PLCLxMS stents in PBS solution at different time points. | Nature Communications

Fig. 3: Staged in vitro degradation behavior of the PLCLxMS stents in PBS solution at different time points.

From: Mechanically robust neuroprotective stent by sequential Mg ions release for ischemic stroke therapy

Fig. 3

A Schematic diagram of Mg2+ release and degradation of PLCLxMS stent struts from cross-sectional perspective. B Staged-cumulative release curve of Mg2+ at different stages. C Staged-Mg2+ release rate over 56 days. D Surface and cross-sectional morphology of the PLCL10MS stents after immersion in PBS for 7 days. E Simulation of Mg2+ dissolution and concentration change in PLCL5MS composites. F Simulated release curves of Mg2+ during immersion of composites with varying MgSO4 contents, based on diffusion theory. Source data and exact P values are provided as a Source data file. One-way analysis of variance (ANOVA) with a Tukey/Games-Howell post hoc test for multiple comparisons. Sample size: n = 3 biologically independent replicates. **P < 0.01, ***P < 0.001, Burst vs. Fast group; # P < 0.05, ## P < 0.01, ### P < 0.001, Fast vs. Stable group; §§ P < 0.01, §§§ P < 0.001, Stable vs. Burst group. Data are presented as mean values ± SD.

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