Fig. 6: In vitro neuroprotection analysis using the OGD/R cell model.
From: Mechanically robust neuroprotective stent by sequential Mg ions release for ischemic stroke therapy
A Schematic of the cell OGD experiment. B Cell viability was assessed by CCK-8 assays. C Relative LDH concentration released from the neuron to the supernatant. D Typical images of intracellular Ca2+ observed by fluorescent microscopy; scale bars: 20 µm. E Quantification of relative fluorescence intensity of intracellular Ca2+. F Relative fluorescence intensity of ROS in neurons. G Changes in cell apoptosis detected by flow cytometry. H Quantification of apoptosis rate from (G). Source data and exact P values are provided as a Source data file. One-way analysis of variance (ANOVA) with a Tukey/Games-Howell post hoc test for multiple comparisons. Sample size: n = 5 biologically independent replicates. *P < 0.05, **P < 0.01, ***P < 0.001 vs. OGD/R group. NS, not significant. Data are presented as mean values ± SD.
