Fig. 8: Behavioral evaluation of tMCAO rat models implanted with PLCLxMS wires after ischemia/reperfusion injury.
From: Mechanically robust neuroprotective stent by sequential Mg ions release for ischemic stroke therapy
A Longa score assessment. B, C Results from the Rotarod test. D–F Adhesive contact and removal test performance before stroke and up to 14 days post-stroke. G Open field test conducted 7 days post-stroke. H Walking distance and time in the open field. I Magnesium concentration in the blood and ipsilateral infarction brain (IIB) of rats at 1 and 7 days post-implantation of PLCLxMS wires. Source data and exact P values are provided as a Source data file. Two-way analysis of variance (ANOVA) with a Tukey/Games-Howell post hoc test for multiple comparisons. Sample size: n = 12 for neurological tests, biologically independent replicates; n = 3 for magnesium content measurement tests, biologically independent replicates. **P < 0.01, ***P < 0.001, tMCAO+PLCL5MS or tMCAO+PLCL10MS vs. tMCAO group; # P < 0.05, ## P < 0.01, ### P < 0.001, tMCAO+PLCL5MS or tMCAO+PLCL10MS vs. tMCAO+PLCL group; § P < 0.05, §§ P < 0.01, §§§ P < 0.001, tMCAO+PLCL10MS vs. tMCAO+PLCL5MS. Data are presented as mean values ± SD.
