Fig. 3: Model of bacteria-phage-macrophage-neutrophils interaction in the lungs.
Individual model predictions and data for 3 mice from each group ranked in columns with corresponding headers. Bacteria are in red, phage in green, alveolar macrophage (AM) in light blue, and lung neutrophils in dark blue. Lines are model-based individual dynamics, dots are bacterial densities, triangles are phage concentrations, crossed squares are lung neutrophils and squares are AM. The light red horizontal dashed lines represent the limit of quantification (LOQ) for bacterial density (LOQ = 5.6 log10 CFUeq/mL), light red circles crossed by this line at their center are below the limit of quantification (BLQ) of bacterial density and light red lines are BLQ of bacterial load model-based predictions (i.e., the discrepancy between data and model cannot be evaluated from this plot in case of BLQ data).
