Fig. 5: Lactate induces transcriptome sequencing and differential gene analysis in K. pneumoniae. | Nature Communications

Fig. 5: Lactate induces transcriptome sequencing and differential gene analysis in K. pneumoniae.

From: Lactate promotes invasive Klebsiella pneumoniae liver abscess syndrome by increasing capsular polysaccharide biosynthesis via the PTS-CRP axis

Fig. 5

a Volcano map showing differentially expressed genes in Kp9925 cultured in LB versus Lac-LB. b KEGG pathway enrichment analysis of differentially expressed genes. c Validation of gfrA, gfrB, gfrC and gfrD expression in 10 K. pneumoniae isolates cultured in LB and Lac-LB. For (a, b) Fisher’s exact test was used to test significance and adjusted by Benjamini and Hochberg. For panel c, statistical analysis was conducted using a two-sided independent-samples t-test. Error bars represent the mean ± SD. Source data are provided as a Source Data file.

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