Table 1 Risk factor analysis of the occurrence of IKPLAS

From: Lactate promotes invasive Klebsiella pneumoniae liver abscess syndrome by increasing capsular polysaccharide biosynthesis via the PTS-CRP axis

Variables

 

Univariate analysis

Multivariate analysis

  

OR

95%CI

P value

OR

95%CI

P value

Demographics

 Age

 

1.040

1.002–1.080

0.041

1.010

0.956–1.068

0.716

 Gender: male

 

1.311

0.493–3.485

0.587

   

Underlying diseases

 Diabetes mellitus

 

3.651

1.266–10.53

0.017

2.172

0.466–10.112

0.323

 Hypertension

 

1.683

0.630–4.491

0.299

   

 Coronary heart disease

 

0.607

0.103–3.563

0.580

   

 Chronic liver diseases

 

2.327

0.672–8.060

0.183

   

 Chronic kidney diseases

 

0.821

0.209–3.219

0.777

   

 Biliary tract disease

 

0.381

0.071–2.041

0.260

   

Laboratory test

 WBC (109/L)

 

0.982

0.868–1.112

0.776

   

 CRP (mg/L)

 

1.005

0.996–1.013

0.278

   

 Neu (%)

 

0.998

0.963–1.035

0.910

   

 Hb (g/L)

 

0.990

0.965–1.016

0.435

   

 AST (U/L)

 

1.002

0.980–1.025

0.843

   

 ALT (U/L)

 

1.003

0.985–1.021

0.747

   

 HbA1c

 

1.527

1.054–2.211

0.025

   

 PCT (ng/mL)

 

1.014

0.971–1.058

0.529

   

 Lactate (mmol/L)

 

3.210

1.485–6.937

0.003

4.547

1.488–13.89

0.008

 PT (s)

 

0.938

0.621–1.418

0.761

   

 APTT (s)

 

1.003

0.896–1.123

0.955

   

Abscess size (cm)

 

1.138

0.926–1.399

0.219

   

Medical history

 Cephalosporins

4th gen

0.571

0.217–1.503

0.256

   

 Fluoroquinolones

levofloxacin

0.797

0.290–2.188

0.660

   
 

moxifloxacin

0.137

0.035–0.531

0.004

0.087

0.009–0.875

0.038

 Carbapenems

imipenem

0.496

0.136–1.803

0.287

   
 

meropenem

0.607

0.103–3.563

0.580

   

 Metronidazole

 

0.431

0.120–1.544

0.196

   

 Cephamycins

 

1.795

0.369–8.719

0.468

   

 Aztreonam

 

0.733

0.161–3.350

0.689

   

Number of puncture

 

3.511

1.406–8.770

0.007

3.050

1.172–7.937

0.022

length of stay

 

1.028

0.981–1.077

0.247

   
  1. Bolded P values indicate statistically significant differences (P < 0.05).