Fig. 6: Analysis of diffusion data upon actin modulation. | Nature Communications

Fig. 6: Analysis of diffusion data upon actin modulation.

From: Concurrent diffusion of nicotinic acetylcholine receptors and fluorescent cholesterol disclosed by two-colour sub-millisecond MINFLUX-based single-molecule tracking

Fig. 6

Ensemble-averaged, time-averaged mean square displacement (EA-TA-MSD) curves determined for all trajectories (Brownian and subdiffusive) of CF®680R-BTX and fPEG-Chol with and without perturbation of the subcortical actin meshwork by CK-666, as labelled. The motional states were classified into three categories: free (orange, upper panels), confined (green, middle panels), and hop-like (red, lower panels) diffusion according to ref. 41 and ref. 40. S denotes the confinement strength for the hopping diffusion, defined as the \({D}_{\mu }/{D}_{M}\) ratio, and the black lines in the panels of the upper two rows give the fits. The dotted lines in the panels of the lower row correspond to the expected MSD for pure diffusion with Dµ and DM. Source data are provided as a Source Data file.

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