Table 1 Sample characteristics

From: Synaptic loss pattern is constrained by brain connectome and modulated by phosphorylated tau in Alzheimer’s disease

Cross-sectional sample

 

CU Aβ- (n = 54)

CU Aβ + (n = 9)

MCI Aβ + (n = 28)

Dementia Aβ + (n = 54)

P value

Age, years

65.15 (7.95)

70.67 (5.85)

71.21 (9.18)

68.57 (7.64)

0.007

Sex, (male/female)

15/39

2/7

12/16

21/33

0.391

Education, years

13.03 (2.67)

12.78 (3.03)

12.20 (3.48)

9.52 (3.47)

3.84×10⁻7

MMSE

28.68 (1.36)

27.22 (2.28)

26.19 (1.71)

15.47 (5.30)

7.38×10⁻42

ApoE ε4 status (pos/neg)

14/39

3/5

16/12

33/19

0.001

Longitudinal sample

  

CU Aβ + (n = 2)

MCI Aβ + (n = 7)

Dementia Aβ + (n = 9)

value

Age, years

 

73.00 (4.24)

71.14 (7.84)

72.11 (8.12)

0.946

Sex, (male/female)

 

1/1

1/6

3/6

 

Education, years

 

14.00 (2.83)

10.71 (4.50)

10.00 (2.92)

0.393

MMSE

 

28.00 (2.83)

25.86 (1.77)

17.67 (5.31)

0.002

ApoE ε4 status (pos/neg)

 

1/0

5/2

6/3

 

SV2A-PET follow-up years

 

1.07 (0.05)

1.22 (0.38)

1.17 (0.13)

0.766

  1. The two -sided p values for continuous variables are determined by the ANOVA test, and those for categorical variables are determined by the chi-square test.
  2. MMSE Mini-Mental State Exam.