Fig. 4: TIVelo’s delineation of two lineages in intestinal organoid.
From: TIVelo: RNA velocity estimation leveraging cluster-level trajectory inference
a Comparative velocity stream plots produced by TIVelo, UniTVelo, and veloVI. b The cluster graph after graph pruning and main path selection. The end cluster Enterocytes is selected as the origin node. c The \(\tilde{u}\)-\(\tilde{s}\) variation along the main path and the linear tree model constructed for gene Muc13, with the orientation score of primary rising/falling section annotated below. The colorbar indicates the cell type, which is identical to the annotation in (a). d Velocity fitting for five different genes from TIVelo. For each gene, the velocity direction of each cell generally points to Enterocytes from Stem cells.
