Fig. 2: Deletion of three lncRNAs reduce fertility and the number of progenitor zone nuclei. | Nature Communications

Fig. 2: Deletion of three lncRNAs reduce fertility and the number of progenitor zone nuclei.

From: Three lncRNAs promote PUM protein condensation and germline differentiation

Fig. 2

a Average self-progeny number of the indicated genotypes. Note the additive effect of lncRNAs deletions. N values represent worms and are marked on the columns. b Average number of nuclei in the progenitor zone in gonads of the indicated genotypes. Note the similar effects of 3xlnc and ectopic FBF-2 expression. N values represent gonads and are marked on the columns. c Distal side of wild-type (top) and 3xlnc (bottom) gonads stained with pH3 (red) and DAPI (white). Dashed lines indicate the border between progenitor zone and early meiotic stages. d Average mitotic index of wild type and 3xlnc. N values represent gonads and are marked on the columns. Two tailed Mann Whitney P value: NS: Not Significant, *< 0.05, **< 0.01, ***< 0.001, ****< 0.0001. Error bars indicate standard error. Gray x’s on the plot represent individual measurements. Scale bar = 10 μM. Source data are provided as a Source Data file.

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