Fig. 3: Condition-specific and shared patterns of reQTLs across multiple stimuli. | Nature Communications

Fig. 3: Condition-specific and shared patterns of reQTLs across multiple stimuli.

From: Gene expression QTL mapping in stimulated iPSC-derived macrophages provides insights into common complex diseases

Fig. 3

a Proportions of reQTLs for every stimulated condition that were found in a single condition only (column 1) or detected in 2 or more stimulated conditions (columns 2–22). Colour intensity reflects the percentage of reQTLs in a given condition that were also detected in at least one other stimulated condition. Columns represent the number of conditions in which an reQTL was detected. b Cumulative percentage of detected reQTLs (red line and points, left hand y axis) and reQTL detection rate (blue boxplots, right hand y axis) versus the number of conditions in which an reQTL was detected. Box plots represent the median (centre line), the first and third quartiles (bounds of the box), and the whiskers, which extend to the smallest and largest values within 1.5x the interquartile range from the bounds of the box. Data points outside this range are plotted as outliers. The cumulative percentage of detected reQTLs (red line, left-hand y-axis) was calculated as the running sum of the mean detection rate across conditions. The x-axis indicates the number of stimulated conditions in which a reQTL was detected, and the right-hand y-axis shows the detection rate. All box plots are based on n = 22 stimulated conditions.

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