Fig. 3: FG1 and FG2 repeats of RanBP2 bound to Crm1. | Nature Communications

Fig. 3: FG1 and FG2 repeats of RanBP2 bound to Crm1.

From: Structural basis for a nucleoporin exportin complex between RanBP2, SUMO1-RanGAP1, the E2 Ubc9, Crm1 and the Ran GTPase

Fig. 3

A EM density for RanBP2 FG1 (contoured at level 6) overlaid with model to highlight interactions with Crm1 HEAT repeats 14–16, depicted in cartoon representation (left panel); FG1 residues in stick representation and Crm1 as surface representation to emphasize deep pockets on its surface (second panel); the FG1-Crm1 interface with side chains and potential hydrogen bonds shown (dashed lines, third and fourth panels). B EM density (contoured at level 5.5) and RanBP2 FG2 residues highlighting interactions with Crm1 HEAT repeats 2–7, depicted in cartoon representation (left panel). Similar view of FG2 model with Crm1 depicted as surface representation to emphasize deep pockets on its surface (right panel). C FG2 (stick representation) interactions with Crm1 HEAT repeats 2–5 cartoon and stick representation for side chains) with potential hydrogen bonds depicted as dashed lines. D Detailed view of the interface between FG2 and Crm1 HEAT repeats 4–7 depicted as in panel C.

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