Fig. 5: Metabolic activity of choroid plexus as a function of age.
a Stable isotope tracing was used to assess the metabolic activity of choroid plexus compared to other tissues (c) and as a function of age (d). b Oxidative [U-13C]glucose metabolism was determined by the cycling ratio being a relative measure of tricarboxylic acid (TCA) cycle activity. c Tissue-specific metabolic activity of lateral choroid plexus (3 M rats, n = 6 (small intestine (dark pink), skeletal muscle (pink), proximal tubule (blue)) or 7 (choroid plexus (green), cerebral cortex (yellow)) rats). d Metabolic activity of lateral choroid plexus as a function of age (n = 6 rats in age group). 1 M; turquoise, 3 M; green, 6 M; orange, 12 M; red, 18 M; purple, 24 M; grey. Data are presented as mean ± SEM, and statistical significance was tested with one-way ANOVA followed by Tukey’s multiple comparisons test. Asterisks denote statistical significance (*P < 0.05). Non-significance is not illustrated for clarity. Source data are provided as a Source Data file and exact P-values in Supplementary Data 2.
