Fig. 2: Preparation and characterization of APPC. | Nature Communications

Fig. 2: Preparation and characterization of APPC.

From: Near-infrared light-driven metabolic reprogramming of synoviocytes for the treatment of rheumatoid arthritis

Fig. 2

a Synthetic route of APPC. b, c Hydrodynamic diameter and zeta potential of AR, APP, APPC and APPC/pHO-1, respectively. d TEM images of AR, APP and APPC. Scale bar: 50 nm. e UV-vis absorption spectra of AR, APP and APPC. f Temperature change curves of PBS, AR, APP and APPC under NIR irradiation (2.0 W/cm2) over time. g Temperature change curves of APPC (200 μg/mL) under various NIR radiation intensities. h Temperature change curves of different APPC concentrations under NIR irradiation (2.0 W/cm2) over time. i TEM and EDS mapping of APPC/pHO-1 nanoparticles. Scale bar: 25 nm. j, k XPS spectra of AR, APP, APPC and APPC/pHO-1. (l, m) The binding and condensation ability of APP and APPC with pHO-1 at different w/w ratios. Data are presented as mean value ± SD (b, c, f–h, n = 3 independent experiments). i, l, m Representative images of three biologically independent experiments with similar results are shown. Source data are provided as Source Data files.

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