Table 1 Particle size and thermostability of recombinant A(H5N1) HA nanoparticles

From: Single-dose avian influenza A(H5N1) Clade 2.3.4.4b hemagglutinin–Matrix-M® nanoparticle vaccine induces neutralizing responses in nonhuman primates

Influenza strain

Dynamic light scattering

Differential scanning calorimetry

Z-avg diameter (nm)

PDI

Tm (°C)

ΔH (kcal mol−1)

Tm1

Tm2

ΔH1

ΔH2

A(H5N1) A/AW/SC/2021 HA

34.78 ± 0.28

0.16 ± 0.01

45.55

52.10

72.3

598.0

  1. ΔH, change in enthalpy; PDI polydispersity index; Tm melting temperature; Z-avg Z-average; HA hemagglutinin.
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