Fig. 6: Main steps of the long-range axon synthesis.
From: Generating brain-wide connectome using synthetic axonal morphologies
From an input biological axon, we take the soma as the source point (a), cluster the tufts, and make their common ancestors the target points. The synthetic trunk is created by connecting the targets from the source point with the Steiner tree on a graph method (b, c). The trunk is then post-processed (d) with the addition of noise to reproduce local morphometrics of biological axons. Finally, the tufts are grown (e) at the target points from their topological properties, with the same method as dendrites8.
