Fig. 2: Reaction kinetic models of nanozymes.

a The Michaelis–Menten kinetic model of a single-substrate reaction. Top: Schematic diagram of the reaction process. Bottom: Saturation curve showing the relation between the substrate concentration and reaction rate. b Calculation of the saturation behavior of the multivalent catalyst models E2–E8 for the case where the catalysis is performed by only a single catalytic unit (top) or by two catalytic units (bottom). Figure adapted from Zaupa et al.⁸⁰ c Effect of catalytic unit clustering on the generation of active sites in multivalent models E2 and E4. Each catalytic unit is represented by a black dot (⚫), and each active site is represented by a line connecting two catalytic units (—). Figure adapted from Zaupa et al.⁸⁰ Kinetic models for two substrate reactions: d ping-pong reaction, e random-sequential reaction, f ordered-sequential reaction.