Fig. 4: Sub-clustering analysis on NK cells.

a Visualization through UMAP of 2868 single cells from HV (n = 3), 1732 single cells from IM (n = 9), and 8911 single cells from HLH (n = 17). Cells were sorted into 5 clusters, each marked with a unique color code. b, c Heatmap representing the average expression values of the highly expressed 10 genes (b) and functional genes (c) in each NK cluster. d, e Enriched GO terms for upregulated genes in HLH patients compared to HV (d) and IM (e).