Fig. 4: Exploration of imprinted genes from PSEs and the investigation of POE from PSMR.
From: Mechanism of parent-of-origin effects revealed by multi-omic data in euro-chinese hybrid pigs
a Genome-wide (Autosomal) distribution of PSMRs and PSEs identified in LD with imprinted genes showing significant expression differences between phases labeled in the genomic regions. b Correlation between differential expression levels of imprinted-like genes and differential methylation levels in their promoters in LD. The cor.test function was used to calculate the Pearson correlation coefficient (r) and the corresponding p-values from the two-sided t-test. Red scatter points indicating imprinted genes across various samples. c Tracks for PSMR, DNA methylation levels, and gene expression levels of PEG3 between the paternal and maternal phase in BF and LD. d An example of ADH1C demonstrating phase-specific DNA methylation levels in the promoter region and phase-specific gene expression levels across samples of BF and LD. e Tracks for PSMR, DNA methylation levels, and gene expression levels of ADH1C between the paternal and maternal phases in BF and LD. f Different transcript types of ADH1C in BF and LD. g Expression levels of ADH1C transcripts between the paternal and maternal phase in BF and LD. Source data are provided as a Source Data file.
