Fig. 2: Digital translation of the synthetic operations required for SPPS into χDL blueprints.
From: Universal peptide synthesis via solid-phase methods fused with chemputation

The synthetic chemical steps required to produce complex peptides are summarized in concise χDL digital blueprints, corresponding to the characteristic stages of SPPS. These, in turn, consist of a sequential list of χDL steps, encoding the chemical synthesis of a desired peptide target through specific physical operations to be performed by the automated platform.