Fig. 2: Network analysis shows conserved upregulation of genes involved in antigen processing and presentation in lung structural cells at day 40 post-IAV infection. | Nature Communications

Fig. 2: Network analysis shows conserved upregulation of genes involved in antigen processing and presentation in lung structural cells at day 40 post-IAV infection.

From: Lung structural cells are altered by influenza virus leading to rapid immune protection following re-challenge

Fig. 2

Networks of all significantly enriched gene sets in epithelial cells A, fibroblasts B, and blood endothelial cells C, highlighting significance and gene set interconnectivity. Networks are given for enrichment amongst all significantly differentially expressed genes (p.adjusted <0.05, absolute log2 fold >0.5) between day 10 and naive, and day 40 and naive. Enrichment analysis was performed using Hyper-geometric Gene Set Enrichment on the gene set databases STRING11.5. For each network, nodes represent gene sets and edges represent two gene sets with a Szymkiewicz-Simpson coefficient of at least 0.5. Colors are defined in the Figure.

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