Fig. 6: Intracellular dominance determination. | Nature Communications

Fig. 6: Intracellular dominance determination.

From: Quantifying collective interactions in biomolecular phase separation

Fig. 6

a Homotypic line scans are performed by quantifying dilute phase concentrations of component A while varying the total concentration of component A (illustrated by yellow-purple colour gradient). b Homotypic response function of G3BP1 in cellulo from ref. 42. c Comparison of homotypic response functions of opto-protein (opto-FUS … green, opto-FUS mutant 5Y > S … light green, opto-G3BP1 … blue) fusion constructs intracellularly from refs. 42,43. d Dominance fraction comparison of different proteins in (c). Data are presented as mean ± SD, parameter errors are estimated by repeated perturbation on fitting data and quantifying the spread of best-fit parameters. Source data are provided as a Source Data file.

Back to article page