Fig. 5: BAT transplantation alters pathways involved in ER stress and fibrosis in the heart. | Nature Communications

Fig. 5: BAT transplantation alters pathways involved in ER stress and fibrosis in the heart.

From: 12,13-diHOME protects against the age-related decline in cardiovascular function via attenuation of CaMKII

Fig. 5

a Heat maps comparing young (3 months old), aged (24 months old) and +BAT aged male mice. b, c Gene ontology analysis of pathways altered among young (3 months old; n = 7), aged (24 months old; n = 9) and +BAT aged male mice (n = 5). Gene ontology enrichment analysis was performed using Metascape. P-values were calculated using the cumulative hypergeometric test and adjusted for multiple comparisons using the Benjamini-Hochberg method (b, c).

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