Fig. 6: The Rbl system from C. rodentium is absent from the E. coli species.

a Maximum likelihood tree depicting the core-genome phylogeny of 949 E. coli isolates built from 245,518 core-genome single-nucleotide polymorphisms, called against str. EDL933 is a reference chromosome. Phylogeny is rooted according to the actual root by Escherichia fergusonii ATCC 35469 (omitted for visualisation). The six main phylogroups (A, B1, B2, D, E, and F) are illustrated as coloured branches. Branch lengths and scale represent the number of nucleotide substitutions per site. b Presence/absence of the rbl locus (ROD_24811-61 from C. rodentium str. ICC168) is based on uniform nucleotide coverage at each 100 bp window size. The heat map illustrates coverage as ≥80% in blue, ≥50% in yellow, and ≥1% in grey. The clustering of isolate sequence types (ST) is indicated on the right. Genome accession numbers are provided as a Source Data file.