Fig. 4: Theta-phase locking, spike numbers, and theta power across brain regions.
From: Theta-phase locking of single neurons during human spatial memory
A–D Theta-phase locking, number of spikes, and theta power in different brain regions during baseline (brown), encoding (blue), and recall (orange). Analyses in (A–D) were performed with 210 neurons from the amygdala (AMY), 130 from the entorhinal cortex (EC), 125 from the hippocampus (HC), 76 from the parahippocampal cortex (PHC), and 92 from the temporal pole (TP). A Percentages of units with significant phase locking. Numbers at top indicate the total number of neurons per region. The percentage of cells with significant phase locking varied between the different brain regions (χ2 tests: baseline, χ2(4) = 15.327, Pcorr. = 0.012; encoding, χ2(4) = 16.198, Pcorr. = 0.008; recall, χ2(4) = 13.729, Pcorr. = 0.025; n = 666; Bonferroni corrected for three tests). B Pairwise phase consistency (PPC) across units. Bars show mean PPC values; dots represent PPC values of individual neurons. Y-axis is expanded between 0 and 0.1 to highlight the range containing most data points. PPC values differed between brain regions (ANOVA for linear mixed-effects model: fixed effect of region, F(4) = 21.347, P < 0.001). C Number of spikes per region, across neurons. Box plots show medians, 25th and 75th percentiles, and outliers as dots. Spike counts did not differ between medial temporal lobe regions (Kruskal–Wallis tests: baseline, H(4) = 8.135, Pcorr. = 0.260; encoding, H(4) = 4.308, Pcorr. = 1; recall, H(4) = 10.161, Pcorr. = 0.113; Bonferroni corrected for three tests). D Log-transformed power assigned to the spikes of each neuron. Bars show mean values; dots represent values of individual neurons. Spike-associated theta power varied between medial temporal lobe regions (ANOVA for linear mixed-effects model: fixed effect of region, F(4) = 204.063, P < 0.001). Source data are provided as a Source Data file.
