Fig. 6: Induced reminiscences in non-fusiform regions connected to the fusiform gyrus (FG). | Nature Communications

Fig. 6: Induced reminiscences in non-fusiform regions connected to the fusiform gyrus (FG).

From: The anterior-posterior gradient of the fusiform gyrus modulates the transition between mnemonic and perceptual features during reminiscences

Fig. 6

a Connection probabilities from non-FG sites to both FG and non-FG regions. Pink and blue dashed lines indicate medians. b FG connections stronger than non-FG (Two-sided Wilcoxon test: Z = –4.815, p = 1.473 × 10−6, n = 52). c, d Responsive regions (RR, n = 52) showed stronger FG connectivity than non- responsive regions (nonRR, n = 143; p = 2.086 × 10−11, Two-sided Mann-Whitney U test). e IOR/EOH sites (n = 36/16) differentially connected to FG subregions (Bonferroni-corrected p values anterior to posterior: 1.000, 0.126, 0.002, 0.011, 0.037, 0.002, 0.653; two-sided Mann–Whitney U test). f IOR exhibited higher connectivity selectivity than EOH (p = 0.005, Two-sided Mann-Whitney U test). g Oriented selectivity index along FG’s anterior-posterior axis. Gray dots: individual data; blue dots: group medians. h ROC analysis of IOR/EOH discrimination via FG anterior-posterior connectivity. Shaded error bands represent 95% confidence intervals. i Connection probabilities from IOR and EOH (n = 21/5) sites to fusiform subregions in Patient 22 (n = 26). Bonferroni-corrected p values (two-sided Mann-Whitney U test, anterior to posterior: 1.000, 0.717, 0.015, 0.010, 0.042, 0.009, 0.885). j Connectivity selectivity index between IOR and EOH in Patient 22 (p = 0.0014, two-sided Mann-Whitney U test). k The oriented selectivity index along the anterior-posterior axis of FG in Patient 22. l ROC analysis distinguishing IOR vs. EOH based on connectivity along the anterior-posterior axis in Patient 22 (p = 0.001, AUC = 0.971, one-sided permutation test). m Proportion of the top 30 brain regions strongly connected to non-fusiform responsive sites. n Distribution of the top 30 probabilities of connections in IOR and EOH, Bonferroni-corrected p values. Numbers in legend indicate subregion positions. IOR Internally-oriented Reminiscences, EOH Externally-oriented Hallucinations, CC Cingulate Cortex, FL Frontal Lobe, LTL Lateral Temporal Lobe, PL Parietal Lobe, Other = regions not classified into these areas. Box plots: center = median; box = 25th–75th percentiles; whiskers = ±1.5 × the interquartile range; outliers plotted individually. Significance: *p < 0.05, **p < 0.01, ***p < 0.001. Source data are provided as a Source Data file.

Back to article page