Fig. 1: Trial profile.

The immunogenicity PPS analysis set included all participants who received two doses within the preset time window, had no major protocol violations, and had pre- and post-vaccination immunogenicity data available. 6 participants were excluded from immunogenicity PPS analysis set because of the second vaccination time beyond the time window, with 5 in LZ901 group and 1 in HZ/su group, see supplementary table 9. PPS, per-protocol set.