Fig. 4: The frequencies of cytokine-producing T cells per 105 CD8+ T cells. | Nature Communications

Fig. 4: The frequencies of cytokine-producing T cells per 105 CD8+ T cells.

From: Immunogenicity and safety of a recombinant gE-Fc fusion protein subunit vaccine for herpes zoster in adults ≥50 years of age: a randomised, active-controlled, non-inferiority trial

Fig. 4

The frequencies of cells secreting IFNγ, TNFα, IL-2, and CD40L from CD8+ T cells in LZ901 group (n = 141) and HZ/su (n = 136) group. The box plots show the median (middle line) and the first and third quartiles (boxes), and the whiskers show the minimun to the maximum value. The numbers indicate the median fold of the frequencies of cytokine-producing CD8+ T cells day 30 postvaccination to that baseline. Differences between groups were analyzed using a two-sided t test after log-transformed T-cell frequency. Day 0, baseline before vaccination; Day 30, day 30 after the second dose. IFN-γ, interferon-γ; IL-2, interleukin-2; TNF-α, tumor necrosis factor-α; CD40L, cluster of differentiation 40 ligand.

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