Fig. 6: Developmental trajectory of TGC. | Nature Communications

Fig. 6: Developmental trajectory of TGC.

From: Mapping the coupling between tract reachability and cortical geometry of the human brain

Fig. 6

A The HCP-D dataset was used to calculate the developmental trajectory of the TGC L1-norm value (n = 590; age range, 8-22). GAM results are shown for each tract. The increate rate of each tract was calculated as the first derivative of the GAM age spline curve. Significant differences were observed by the Mann-Whitney U test between each two tract types, with the two-tailed p-values provided in the corresponding panels (association vs. commissural: p = 5.759e-04; commissural vs. projection: p = 0.4493; association vs. projection: p = 4.447e-05). ***p < 0.001, **p < 0.01, *p < 0.05. B Developmental trajectory of six example tracts. Left in each subfigure: Detailed developmental trajectories of the top six example tracts. Shade regions indicate 95% confidence intervals. Two black dotted lines denote age 14 and 19. Right: TGC L1-norm value for the same tracts at age 14, 19, and 23 in the IMAGEN dataset. Each dot represents an individual, with gray lines connecting repeated measures from the same participant. Half-violin plots display the kernel density of the data distribution. Boxplots within each violin plot show the median (center line), interquartile range (IQR) (box edges). Pair t-test were performed between each pair of ages, with t-values and two-tailed p-values indicated. CG cingulum, UF uncinate fasciculus, MLF middle longitudinal fasciculus, ILF inferior longitudinal fasciculus, SLF_III superior longitudinal fasciculus III, AF arcuate fasciculus. Source data are provided as a Source Data file.

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