Fig. 1: Sequence and secondary structure models for the consensus bacterial guanidine-II riboswitch class and representative vertebrate hits. | Nature Communications

Fig. 1: Sequence and secondary structure models for the consensus bacterial guanidine-II riboswitch class and representative vertebrate hits.

From: Guanidine aptamers are present in vertebrate RNAs associated with calcium signaling and neuromuscular function

Fig. 1

a Updated consensus sequence and structural model for bacterial guanidine-II riboswitches. The consensus was updated from previous models3,55 by examining 1977 distinct bacterial representatives. b Sequence and secondary structure model for a guanidine-II riboswitch aptamer candidate from the CA8 gene of African elephant (Loxodonta africana). c Sequence and secondary structure model for a guanidine-II riboswitch aptamer candidate associated with the PISD gene from the bird Rhinoptilus africanus. d Sequence and secondary structure model for a guanidine-II riboswitch aptamer candidate associated with the CACNA1C gene of common bottlenose dolphin (Tursiops truncatus). Note: Additional hairpins conforming to the guanidine-II aptamer consensus reside near to the examples presented here. Nucleotide numbering for each panel is based on the RNA constructs used for ligand binding assays.

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