Fig. 6: In vivo anti-tumor efficacy and biocompatibility of HTHSG in a colorectal cancer PDX model.
From: A hollow-tube-like hydrospongel for multimodal therapy of advanced colorectal cancer
a Schematic of PDX model establishment and treatment. Created in BioRender. Zhao, J. (2025) https://BioRender.com/37om8bc. b Immunohistochemical analysis for CK, KI67, MLH1, and HER2 in tumor slices from colorectal cancer patients and the PDX model to evaluate their similarity. Scale bar: 100 μm. c Thermal images of PDX tumor-bearing mice during AMF exposure. d Digital images of the excised tumor of the PDX model. Scale bar: 1 cm. e Tumor volumes of colorectal PDX model mice for 4 patients in Groups 1, 2, 3, 4, 5, 6 and 7. f Tumor weights from different colorectal PDX model mice for 4 patients in Group 1, 2, 3, 4, 5, 6 and 7. g Body weight changes across different mouse groups of the PDX model. The data were presented as the mean ± SD (n = 4 mice per group). Source data are provided as a Source Data file.
