Fig. 4: Interpretation of features predictive of early cancer onset. | Nature Communications

Fig. 4: Interpretation of features predictive of early cancer onset.

From: Peripheral blood DNA methylation predicts the early onset of primary tumor in TP53 mutation carriers

Fig. 4

A Model feature importance (SHAP value) for early cancer onset prediction, across all the features. B Feature importance for the TP53 variant-related features. OD oligomerization domain, DBD DNA binding domain, TA transactivation domain. C. Feature importance for the top 20 features. Source data are provided as a Source Data file.

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