Fig. 3: DL stratifies recurrence risk within MRD subgroups.
From: HIBRID: histology-based risk-stratification with deep learning and ctDNA in colorectal cancer
Kaplan-Meier curves showing DFS stratification by DL high-risk and DL low-risk groups for A MRD-positive and B MRD-negative groups, followed by Kaplan-Meier curves showing DFS stratified by with or without ACT treatment in C MRD-positive and DL low-risk, D MRD-negative and DL low-risk, E MRD-positive and DL high-risk and F MRD-negative and DL high-risk subgroups. HR and 95% CI were calculated by the Cox proportional hazard model. P value was calculated using the two-sided log-rank test. Plots were generated using the lifelines package in Python 3.11.5 Source data is provided as a Source Data file. DFS=disease-free survival, DL=Deep Learning, ACT=adjuvant chemotherapy, MRD=molecular residual disease, HR=Hazard ratio, CI=Confidence interval.
