Fig. 5: Deletion of motV increased V. cholerae diarrheaogenicity.
From: Vibrio cholerae motility is associated with inter-animal transmission
A CD1 pups were intragastrically inoculated with the indicated V. cholerae strains and individually housed for 18-hours. The bedding was weighed prior to and after infection to determine fluid discharge. Fluid accumulation in the SI 18-hours post inoculation was measured by comparing the weight of the animal to the weight of the SI. Weight loss was determined by comparing animal weight before and after infection. n = 30 pups (3 litters) randomized between strains. Mean and standard deviation. One-way ANOVA with Tukey’s multiple comparison correction. B CD1 pups were intragastrically inoculated with the indicated V. cholerae strains, returned to dams for care, and monitored until the predetermined 30-hour endpoint. Survival kinetics with two-sided Mantel-Cox test. n = 36 pups (4 litters) randomized between strains. Source data are provided as a Source Data file.
