Fig. 5: Or/In-Se NPs reduces ischemic stroke reperfusion-induced oxidative injury in vivo.
From: Organic-inorganic covalent selenium reversing ischemic reperfusion injury
a Illustrated protocol for Or/In-Se NPs to treat mice in ischemic stroke-reperfusion injury. The icons of the mouse and brain tissues are created with BioRender.com. b Digital images of ischemic stroke mice with different treatments for evaluating action capability. Neuronal function evaluation of the treated MCAO mice by behavioral tests, including (c) tail suspension test, (d) Rota-Rod test and (e) neurological scores at different time points (mean ± SD, n = 4 biologically independent samples, One-Way ANOVA test, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001. f Representative brain tissue images of TTC staining in MCAO mice with different treatments for 72 h (n = 3 biologically independent samples). g MRI T2 images of MCAO mice at different brain layers with 72 h-treatment (Red cycle: Infarct area, n = 3 biologically independent samples). Source data are provided as a Source Data file.
