Fig. 2: The molecular heterogeneity and functional analysis of the LNs subtypes. | Nature Communications

Fig. 2: The molecular heterogeneity and functional analysis of the LNs subtypes.

From: Lymph nodes molecular subtypes unravel lymph nodes heterogeneity and clinical implications in colorectal cancer

Fig. 2

A Gene expression differences between LNs subtypes from BJ cohort (n = 173). Adjustment p value was obtained using DESeq2 which utilized Wald test. Gene expression patterns of target DEGs across LNs subtypes (n = 173): B up-regulated DEGs; C down-regulated DEGs. D Venn diagram of DEGs between different subgroups (n = 173). Over-representation enrichment analysis for the target DEGs based on the Metascape enrichment method (n = 173): E up-regulated DEGs between NLN_C4 and NLN_C1; F down-regulated DEGs between NLN_C4 and NLN_C1. LNs lymph nodes, DEGs differentially expressed genes, Meta metastatic, Non-meta Non-metastatic.

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