Fig. 3: Substrate scope of ethers.
From: Post-functionalization of polyethers by photoinduced C–H amidation via polar-radical relay
Reactions were carried out under N2 atmosphere using amidating reagent (0.2 mmol), ether (1.0 mmol), n-C4F9I (5.0 mol%), blue LED (427 nm, Kessil Lamps) and EtOAc at RT for 12 h. For 6-membered cyclic ethers, MeCN/EtOAc (1:1) was applied, using 10.0 equiv of ether and 20.0 mol% of n-C4F9I. For benzo-fused or benzylic ethers, EtOAc was applied, using 1.2 equiv of N-chloro-N-sodio-carbamate (based on 1.0 equiv of ether) and 2.0 mol% of NIS instead of n-C4F9I. a2.0 Equiv of ether was used. bN-Chloro-N-sodio-carbamate (0.2 mmol), ether (0.4 mmol), and n-C4F9I (5.0 mol%) were used. c1.0 Equiv of ether was used. d10.0 mol% of n-C4F9I was used. e1.2 Equiv of ether was used.
