Fig. 7: CZP@LC inhibits adipogenesis via interference with lipid synthesis in vitro and in vivo. | Nature Communications

Fig. 7: CZP@LC inhibits adipogenesis via interference with lipid synthesis in vitro and in vivo.

From: Remodeling adipocytes’ lipid metabolism with a polycation loaded enzyme-active framework reverses osteoporotic bone marrow

Fig. 7

A, B Representative images and quantification of ORO staining in BMSCs after ADI with different treatments (n = 5 independent experiments). C–E Representative images and quantification of BODIPY and LPO staining in BMAds subjected to different treatments n = 5 independent experiments). F–H qPCR analysis of gene expression in BMSCs after various ADI treatments (n = 3 independent experiments). I, J Immunofluorescence and quantitative analysis of PPARγ in femoral sections and enlarged images (n = 5 mice). K, L Representative images and quantitative analysis of ORO staining in femoral sections (n = 5 mice). The data were expressed as the means ± SDs. Statistical significance was determined by one-way ANOVA. *p < 0.05, **p < 0.01, ***p < 0.001.

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