Fig. 8: Inputs across three patterning axes in the OPC are integrated to generate neural diversity.
From: Concurrent temporal patterning of neural stem cells in the fly visual system
a The developmental birth windows of uni- and multi-columnar neurons over the course of neurogenesis. b A combination of NE temporal (i.e., Imp, Syp), NB temporal (i.e., Hth, Ey, Slp, D, Tll), spatial (not pictured) and binary Notch status contributes to the generation of neural diversity in the medulla. c Concurrent temporal patterning mechanisms can act to generate neural diversity in systems with distinct symmetric (produce two progenitors; P–P) and asymmetric (produce a progenitor and neuron; P–N) progenitor division modes.
