Fig. 3: Association between asymmetry in Aβ and tau distribution. | Nature Communications

Fig. 3: Association between asymmetry in Aβ and tau distribution.

From: Hemispheric asymmetry of tau pathology is related to asymmetric amyloid deposition in Alzheimer’s Disease

Fig. 3

a Aβ and tau laterality averaging the PET uptake over the whole hemisphere; b Regional-specific asymmetries in Aβ and tau. Panel a shows a regression line with 95% confidence interval, with statistical annotation indicating the standardized effect size and significance of Aβ laterality as a predictor of tau laterality in an ordinary least squares multiple linear regression model (global tau laterality ~ age + sex + global Aβ laterality). Panel b depicts similar models for all homotopic regions, with significance levels FDR-corrected and visualized on brain surface and bar plots. Aβ amyloid-beta; *, pFDR < 0.05; **, pFDR < 0.01; ***, pFDR < 0.001.

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