Fig. 8: An overview of the data processing steps and analyses.

PET positron emission tomography, dMRI diffusion magnetic resonance imaging, RSfMRI resting-state functional magnetic resonance imaging, FMM flutemetamol, SUVR standardized uptake value ratio, Meta-ROI meta region of interest, EC entorhinal cortex, LA left tau asymmetric, S tau symmetric, RA right tau asymmetric, DTI diffusion tensor imaging, MD mean diffusivity, FA fractional anisotropy, FMin Forceps Minor, CC Corpus Callosum, FMaj Forceps Major, ACT anatomically constrained tractography, SIFT2 spherical-deconvolution informed filtering of tractograms, LH/RH left/right hemisphere, SC structural connectivity, BOLD blood-oxygen-level-dependent imaging, FC functional connectivity, Aβ amyloid-beta.