Fig. 6: Uniform manifold approximation and projection algorithm. | Nature Communications

Fig. 6: Uniform manifold approximation and projection algorithm.

From: Best practices and tools in R and Python for statistical processing and visualization of lipidomics and metabolomics data

Fig. 6

A–D Uniform Manifold Approximation and Projection algorithm. A Examples of simplices. B High-dimensional topological representation. C Low-dimensional topological representation. D The layout of the low-dimensional topological representation is optimized to maximally preserve the structure of the high-dimensional graph. E, F 2D & 3D UMAP scatter plots for a dataset composed of lipid concentrations analyzed via the LC-MS in plasma samples of patients with gout (red dots) and healthy subjects (blue dots). Figure adapted from86,87 and Created in BioRender. Demeulemeester, J. (2025) https://BioRender.com/xcvtpps. The dataset has been published by Kvasnička et al. in their manuscript Alterations in lipidome profiles distinguish early-onset hyperuricemia, gout, and the effect of urate-lowering treatment127.

Back to article page